Targeted analysis of oxygenated polyunsaturated fatty acid derivatives spanning inflammatory signaling, vascular regulation, cytochrome P450 epoxygenase metabolism, and pathways associated with inflammation resolution.
Oxylipin pathway explorer
Choose an analyte below for its pathway context, or open the pathway graphic to explore the measured mediators in relation to their common fatty acid precursors. Only gold-outlined nodes are measured.
Click a compound to update its context below the map.
Interactive oxylipin pathway map
Gold: measured analytes · Gray/dashed: unmeasured precursors or intermediates · Arrows: pathway steps or explicitly labeled multistep relationships. Related isomers are not assumed to be interchangeable.
Arachidonic acid (AA) · COX, LOX, CYP
Linoleic acid (LA) · CYP epoxide and HODE branches
Representative pathway relationshipBiological context and interpretationAssay consideration
Biological significance depends on sample matrix, detection/quantitation limits, stereoisomer specificity and pre-analytical handling. Measured concentration does not by itself establish pathway flux or enzyme activity.
Interpretation notes: AA, LA, EPA and DHA are precursor context nodes, not analytes in this 22-target panel. The abbreviation 10,17-DiHDHA does not specify the stereochemistry needed to identify protectin D1 or PDX. Some pathways include unmeasured hydroperoxides, epoxides and intermediate prostanoids; simplified arrows indicate these where relevant. Consult the Core for method-specific isomer resolution and assay validation.