:root {
  --ta-navy: #071d2f;
  --ta-navy-2: #0d2d46;
  --ta-gold: #cfb87c;
  --ta-blue: #1b66b1;
  --ta-ink: #172331;
  --ta-muted: #5c6976;
  --ta-line: #d9e1e7;
  --ta-soft: #f4f7f9;
  --ta-white: #fff;
}

.targeted-assays-page {
  background: #fff;
  color: var(--ta-ink);
}

/* Hero follows the same visual language as Instruments and Data Analysis. */
.targeted-hero {
  position: relative;
  overflow: hidden;
  color: #fff;
  background:
    radial-gradient(circle at 82% 20%, rgba(207, 184, 124, .16), transparent 23%),
    linear-gradient(135deg, var(--ta-navy), var(--ta-navy-2));
}

.targeted-hero::after {
  content: "";
  position: absolute;
  inset: 0;
  pointer-events: none;
  opacity: .22;
  background-image:
    linear-gradient(rgba(255, 255, 255, .055) 1px, transparent 1px),
    linear-gradient(90deg, rgba(255, 255, 255, .055) 1px, transparent 1px);
  background-size: 44px 44px;
  mask-image: linear-gradient(90deg, #000 0%, transparent 88%);
}

.targeted-hero-inner,
.targeted-page {
  width: min(1180px, calc(100% - 48px));
  margin: 0 auto;
}

.targeted-hero-inner {
  position: relative;
  z-index: 2;
  display: grid;
  grid-template-columns: minmax(0, 1.15fr) minmax(320px, .85fr);
  gap: 54px;
  align-items: center;
  padding: 66px 0 70px;
}

.targeted-kicker,
.targeted-page .approach-kicker,
.targeted-page .eyebrow {
  margin: 0 0 8px;
  color: var(--ta-gold);
  font-size: 13px;
  font-weight: 800;
  letter-spacing: .12em;
  text-transform: uppercase;
}

.targeted-hero h2 {
  max-width: 780px;
  margin: 10px 0 16px;
  font-size: clamp(2.35rem, 3.4vw, 2.75rem);
  line-height: 1.08;
  letter-spacing: -.03em;
}

.targeted-hero p {
  max-width: 760px;
  margin: 0;
  color: rgba(255, 255, 255, .84);
  font-size: 1.16rem;
  line-height: 1.65;
}

.targeted-hero-card {
  padding: 24px 26px;
  border: 1px solid rgba(255, 255, 255, .18);
  border-radius: 14px;
  background: rgba(255, 255, 255, .06);
  box-shadow: 0 18px 38px rgba(0, 0, 0, .18);
}

.targeted-hero-card>strong {
  display: block;
  margin-bottom: 18px;
  color: var(--ta-gold);
  font-size: 13px;
  font-weight: 800;
  letter-spacing: .11em;
  text-transform: uppercase;
}

.targeted-hero-card ul {
  margin: 0;
  padding: 0;
  list-style: none;
}

.targeted-hero-card li {
  margin: 0 0 18px;
}

.targeted-hero-card li:last-child {
  margin-bottom: 0;
}

.targeted-hero-card li strong {
  display: block;
  margin-bottom: 5px;
  color: #fff;
  font-size: 18px;
  line-height: 1.25;
}

.targeted-hero-card li span {
  display: block;
  color: rgba(255, 255, 255, .8);
  font-size: 14px;
  line-height: 1.55;
}

.targeted-page {
  padding: 68px 0 76px;
}

/* Section headings */
.targeted-page .section-title {
  display: flex;
  justify-content: space-between;
  align-items: end;
  gap: 20px;
  margin-bottom: 24px;
}

.targeted-page .section-title h2,
.targeted-page .biocrates-feature h2 {
  margin: 0 0 12px;
  color: var(--ta-navy);
  font-size: clamp(2rem, 2.8vw, 2.2rem);
  line-height: 1.12;
}

.targeted-page .section-title p {
  max-width: 760px;
  margin: 0;
  color: var(--ta-muted);
  font-size: 1.04rem;
  line-height: 1.68;
}

.targeted-page .approach-section {
  margin-bottom: 68px;
}

/* Two primary approaches */
.targeted-page .approach-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 20px;
  margin-top: 30px;
}

.targeted-page .approach-panel {
  padding: 26px;
  border: 1px solid var(--ta-line);
  border-radius: 14px;
  background: #fff;
  box-shadow: 0 8px 24px rgba(10, 31, 50, .05);
}

.targeted-page .approach-panel.biocrates {
  background: var(--ta-soft);
}

.targeted-page .approach-panel h3 {
  margin: 0 0 10px;
  color: var(--ta-navy);
  font-size: 1.45rem;
}

.targeted-page .approach-panel p {
  margin: 0;
  color: var(--ta-muted);
  line-height: 1.62;
}

.targeted-page .approach-facts,
.targeted-page .compound-list,
.targeted-page .biocrates-classes {
  display: flex;
  flex-wrap: wrap;
  gap: 8px;
}

.targeted-page .approach-facts {
  margin: 18px 0 22px;
}

.targeted-page .approach-facts span,
.targeted-page .compound-list span {
  padding: 6px 9px;
  border: 1px solid var(--ta-line);
  border-radius: 6px;
  background: #f8fafc;
  color: #274563;
  font-size: 12px;
  font-weight: 700;
}

/* Focused assay cards */
.targeted-page .assay-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 20px;
  margin-top: 28px;
}

.targeted-page .assay-card {
  display: flex;
  flex-direction: column;
  min-height: 318px;
  overflow: hidden;
  border: 1px solid var(--ta-line);
  border-radius: 14px;
  background: #fff;
  box-shadow: 0 8px 24px rgba(10, 31, 50, .05);
}

.targeted-page .assay-top {
  padding: 24px 24px 0;
}

.targeted-page .tag {
  display: inline-block;
  padding: 5px 8px;
  border: 1px solid #dbc27c;
  border-radius: 5px;
  background: #fbf6e8;
  color: #725300;
  font-size: 11px;
  font-weight: 800;
  letter-spacing: .03em;
  text-transform: uppercase;
}

.targeted-page .assay-card h3 {
  margin: 15px 0 10px;
  color: var(--ta-navy);
  font-size: 1.35rem;
}

.targeted-page .assay-card p {
  margin: 0 0 16px;
  color: var(--ta-muted);
  line-height: 1.58;
}

.targeted-page .compound-list {
  margin: 14px 0 18px;
}

.targeted-page .assay-actions {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 10px;
  margin-top: auto;
  padding: 0 24px 24px;
}

.targeted-page .assay-actions .btn,
.targeted-page .approach-panel .btn,
.targeted-page .biocrates-actions .btn {
  text-decoration: none;
}

.targeted-page .coming {
  opacity: .92;
}

/* Biocrates feature block uses the same navy panel style as site callouts. */
.targeted-page .biocrates-feature {
  margin-top: 68px;
  padding: 30px;
  border-radius: 14px;
  background: var(--ta-navy);
  color: #fff;
  box-shadow: 0 12px 30px rgba(7, 29, 47, .12);
}

.targeted-page .biocrates-feature .eyebrow {
  color: var(--ta-gold);
}

.targeted-page .biocrates-feature h2 {
  color: #fff;
}

.targeted-page .biocrates-feature>p {
  max-width: 900px;
  margin: 0;
  color: rgba(255, 255, 255, .82);
  line-height: 1.65;
  font-size: 1.04rem;
}

.targeted-page .biocrates-metrics {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 14px;
  margin: 26px 0 18px;
}

.targeted-page .biocrates-metric {
  padding: 18px 16px;
  border: 1px solid rgba(255, 255, 255, .18);
  border-radius: 10px;
  background: rgba(255, 255, 255, .06);
  text-align: center;
}

.targeted-page .biocrates-metric strong {
  display: block;
  color: #fff;
  font-size: 28px;
  line-height: 1;
}

.targeted-page .biocrates-metric span {
  display: block;
  margin-top: 7px;
  color: rgba(255, 255, 255, .76);
  font-size: 13px;
}

.targeted-page .biocrates-classes {
  margin: 18px 0 24px;
}

.targeted-page .biocrates-classes span {
  padding: 6px 9px;
  border: 1px solid rgba(255, 255, 255, .18);
  border-radius: 6px;
  background: rgba(255, 255, 255, .07);
  color: #fff;
  font-size: 12px;
  font-weight: 700;
}

.targeted-page .biocrates-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 12px;
}

.targeted-page .biocrates-actions .btn-outline {
  border-color: rgba(255, 255, 255, .45);
  background: transparent;
  color: #fff;
}

/* Supporting note */
.targeted-page .note {
  margin-top: 30px;
  padding: 18px 20px;
  border-left: 4px solid var(--ta-gold);
  background: var(--ta-soft);
  color: var(--ta-muted);
  line-height: 1.6;
}

/* Preserve existing interactive/detail components while restyling them to match. */
.targeted-page .graphic-preview {
  margin: 0 0 20px;
  overflow: hidden;
  border: 1px solid var(--ta-line);
  border-radius: 12px;
  background: #fff;
}

.targeted-page .graphic-preview img {
  display: block;
  width: 100%;
}

.targeted-page .graphic-preview.is-hidden {
  display: none;
}

.targeted-page .btn-button {
  border: 0;
  cursor: pointer;
  font-family: inherit;
  font-size: inherit;
}

.targeted-page .interactive-compounds {
  gap: 10px;
}

.targeted-page .compound-pill {
  padding: 7px 10px;
  border: 1px solid var(--ta-line);
  border-radius: 6px;
  background: #f8fafc;
  color: #274563;
  font-size: 12px;
  font-weight: 800;
  cursor: pointer;
  transition: all .18s ease;
}

.targeted-page .compound-pill:hover,
.targeted-page .compound-pill.active {
  border-color: var(--ta-navy);
  background: var(--ta-navy);
  color: #fff;
  transform: translateY(-1px);
}

.targeted-page .interaction-hint {
  margin-top: -4px !important;
  color: var(--ta-muted);
  font-size: 13px;
}

.targeted-page .bile-acid-layout {
  display: grid;
  grid-template-columns: minmax(0, 1.05fr) minmax(360px, .95fr);
  gap: 22px;
  padding: 0 22px 22px;
  align-items: start;
}

.targeted-page .bile-acid-left {
  min-width: 0;
}

.targeted-page .bile-acid-right {
  position: sticky;
  top: 92px;
}

.targeted-page .compound-detail-layout {
  margin: 0;
}

.targeted-page .compound-detail-panel {
  padding: 22px;
  border: 1px solid var(--ta-line);
  border-radius: 12px;
  background: #fff;
  box-shadow: 0 8px 22px rgba(10, 31, 50, .05);
}

.targeted-page .detail-eyebrow {
  margin-bottom: 8px;
  color: #7b5b00;
  font-size: 11px;
  font-weight: 900;
  letter-spacing: .12em;
  text-transform: uppercase;
}

.targeted-page .compound-detail-panel h4 {
  margin: 0 0 8px;
  color: var(--ta-navy);
  font-size: 22px;
}

.targeted-page .compound-detail-panel h4 span {
  color: var(--ta-muted);
  font-size: 16px;
}

.targeted-page .compound-detail-panel p {
  margin: 0 0 12px;
  color: var(--ta-muted);
  line-height: 1.55;
}

.targeted-page .detail-badges {
  display: flex;
  flex-wrap: wrap;
  gap: 8px;
  margin: 12px 0 16px;
}

.targeted-page .detail-badges span {
  padding: 6px 9px;
  border: 1px solid #dbc27c;
  border-radius: 5px;
  background: #fbf6e8;
  color: #725300;
  font-size: 12px;
  font-weight: 800;
}

.targeted-page .pubchem-link {
  display: inline-flex;
  align-items: center;
  gap: 6px;
  margin: 0 0 16px;
  padding: 9px 12px;
  border: 1px solid var(--ta-line);
  border-radius: 8px;
  background: #f8fafc;
  color: var(--ta-navy);
  text-decoration: none;
  font-size: 13px;
  font-weight: 900;
}

.targeted-page .pubchem-link:hover {
  border-color: var(--ta-navy);
  background: var(--ta-navy);
  color: #fff;
}

.targeted-page .detail-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 14px;
}

.targeted-page .detail-grid div {
  padding: 12px;
  border: 1px solid var(--ta-line);
  border-radius: 9px;
  background: #f8fafc;
}

.targeted-page .detail-grid strong,
.targeted-page .compound-mini-note strong {
  display: block;
  margin-bottom: 6px;
  color: var(--ta-navy);
}

.targeted-page .compound-tooltip {
  position: fixed;
  z-index: 100;
  max-width: 310px;
  padding: 14px 15px;
  border-radius: 10px;
  background: #071f3a;
  color: #fff;
  box-shadow: 0 18px 42px rgba(0, 0, 0, .28);
  pointer-events: none;
  transform: translate(14px, 14px);
  opacity: 0;
  transition: opacity .12s ease;
}

.targeted-page .compound-tooltip.show {
  opacity: 1;
}

.targeted-page .compound-tooltip strong {
  display: block;
  margin-bottom: 6px;
  color: var(--ta-gold);
}

.targeted-page .compound-tooltip p {
  margin: 0;
  color: #e7eef8;
  font-size: 13px;
  line-height: 1.4;
}

@media (max-width: 980px) {

  .targeted-hero-inner,
  .targeted-page .approach-grid,
  .targeted-page .bile-acid-layout {
    grid-template-columns: 1fr;
  }

  .targeted-page .assay-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .targeted-page .biocrates-metrics {
    grid-template-columns: 1fr;
  }

  .targeted-page .bile-acid-right {
    position: static;
  }
}

@media (max-width: 700px) {

  .targeted-page .assay-grid,
  .targeted-page .detail-grid {
    grid-template-columns: 1fr;
  }

  .targeted-page .section-title {
    align-items: flex-start;
    flex-direction: column;
  }
}

@media (max-width: 620px) {

  .targeted-hero-inner,
  .targeted-page {
    width: min(100% - 30px, 1180px);
  }

  .targeted-hero-inner {
    padding: 54px 0 58px;
  }
}